Please use this identifier to cite or link to this item: http://localhost/handle/Hannan/232009
Title: Contrast Enhanced Superharmonic Imaging for Acoustic Angiography Using Reduced Form-Factor Lateral Mode Transmitters for Intravascular and Intracavity Applications
Authors: Zhuochen Wang;K. Heath Martin;Wenbin Huang;Paul A. Dayton;Xiaoning Jiang
Year: 2017
Publisher: IEEE
Abstract: Techniques to image the microvasculature may play an important role in imaging tumor-related angiogenesis and vasa vasorum associated with vulnerable atherosclerotic plaques. However, the microvasculature associated with these pathologies is difficult to detect using traditional B-mode ultrasound or even harmonic imaging due to small vessel size and poor differentiation from surrounding tissue. Acoustic angiography, a microvascular imaging technique that utilizes superharmonic imaging (detection of higher order harmonics of microbubble response), can yield a much higher contrast-to-tissue ratio than second harmonic imaging methods. In this paper, two dual-frequency transducers using lateral mode transmitters were developed for superharmonic detection and acoustic angiography imaging in intracavity applications. A single element dual-frequency intravascular ultrasound transducer was developed for concept validation, which achieved larger signal amplitude, better contrast-to-noise ratio (CNR), and pulselength compared to the previous work. A dual-frequency [Pb(M<sub>g1/3</sub>Nb<sub>2/3</sub>)O<sub>3</sub>]-x[PbTiO<sub>3</sub>] array transducer was then developed for superharmonic imaging with dynamic focusing. The axial and lateral sizes of the microbubbles in a 200-&x03BC;m tube were measured to be 269 and 200 &x03BC;m, respectively. The maximum CNR was calculated to be 22 dB. These results show that superharmonic imaging with a low frequency lateral mode transmitter is a feasible alternative to thickness mode transmitters when the final transducer size requirements dictate design choices.
URI: http://localhost/handle/Hannan/232009
volume: 64
issue: 2
More Information: 311,
319
Appears in Collections:2017

Files in This Item:
File SizeFormat 
7604089.pdf1.65 MBAdobe PDF
Title: Contrast Enhanced Superharmonic Imaging for Acoustic Angiography Using Reduced Form-Factor Lateral Mode Transmitters for Intravascular and Intracavity Applications
Authors: Zhuochen Wang;K. Heath Martin;Wenbin Huang;Paul A. Dayton;Xiaoning Jiang
Year: 2017
Publisher: IEEE
Abstract: Techniques to image the microvasculature may play an important role in imaging tumor-related angiogenesis and vasa vasorum associated with vulnerable atherosclerotic plaques. However, the microvasculature associated with these pathologies is difficult to detect using traditional B-mode ultrasound or even harmonic imaging due to small vessel size and poor differentiation from surrounding tissue. Acoustic angiography, a microvascular imaging technique that utilizes superharmonic imaging (detection of higher order harmonics of microbubble response), can yield a much higher contrast-to-tissue ratio than second harmonic imaging methods. In this paper, two dual-frequency transducers using lateral mode transmitters were developed for superharmonic detection and acoustic angiography imaging in intracavity applications. A single element dual-frequency intravascular ultrasound transducer was developed for concept validation, which achieved larger signal amplitude, better contrast-to-noise ratio (CNR), and pulselength compared to the previous work. A dual-frequency [Pb(M<sub>g1/3</sub>Nb<sub>2/3</sub>)O<sub>3</sub>]-x[PbTiO<sub>3</sub>] array transducer was then developed for superharmonic imaging with dynamic focusing. The axial and lateral sizes of the microbubbles in a 200-&x03BC;m tube were measured to be 269 and 200 &x03BC;m, respectively. The maximum CNR was calculated to be 22 dB. These results show that superharmonic imaging with a low frequency lateral mode transmitter is a feasible alternative to thickness mode transmitters when the final transducer size requirements dictate design choices.
URI: http://localhost/handle/Hannan/232009
volume: 64
issue: 2
More Information: 311,
319
Appears in Collections:2017

Files in This Item:
File SizeFormat 
7604089.pdf1.65 MBAdobe PDF
Title: Contrast Enhanced Superharmonic Imaging for Acoustic Angiography Using Reduced Form-Factor Lateral Mode Transmitters for Intravascular and Intracavity Applications
Authors: Zhuochen Wang;K. Heath Martin;Wenbin Huang;Paul A. Dayton;Xiaoning Jiang
Year: 2017
Publisher: IEEE
Abstract: Techniques to image the microvasculature may play an important role in imaging tumor-related angiogenesis and vasa vasorum associated with vulnerable atherosclerotic plaques. However, the microvasculature associated with these pathologies is difficult to detect using traditional B-mode ultrasound or even harmonic imaging due to small vessel size and poor differentiation from surrounding tissue. Acoustic angiography, a microvascular imaging technique that utilizes superharmonic imaging (detection of higher order harmonics of microbubble response), can yield a much higher contrast-to-tissue ratio than second harmonic imaging methods. In this paper, two dual-frequency transducers using lateral mode transmitters were developed for superharmonic detection and acoustic angiography imaging in intracavity applications. A single element dual-frequency intravascular ultrasound transducer was developed for concept validation, which achieved larger signal amplitude, better contrast-to-noise ratio (CNR), and pulselength compared to the previous work. A dual-frequency [Pb(M<sub>g1/3</sub>Nb<sub>2/3</sub>)O<sub>3</sub>]-x[PbTiO<sub>3</sub>] array transducer was then developed for superharmonic imaging with dynamic focusing. The axial and lateral sizes of the microbubbles in a 200-&x03BC;m tube were measured to be 269 and 200 &x03BC;m, respectively. The maximum CNR was calculated to be 22 dB. These results show that superharmonic imaging with a low frequency lateral mode transmitter is a feasible alternative to thickness mode transmitters when the final transducer size requirements dictate design choices.
URI: http://localhost/handle/Hannan/232009
volume: 64
issue: 2
More Information: 311,
319
Appears in Collections:2017

Files in This Item:
File SizeFormat 
7604089.pdf1.65 MBAdobe PDF