Please use this identifier to cite or link to this item: http://localhost/handle/Hannan/584160
Title: Simultaneous Quantitative Imaging of Electrical Properties and Proton Density From <formula formulatype="inline"><tex Notation="TeX"> B_{1} </tex></formula> Maps Using MRI
Authors: Jiaen Liu;Pierre-Francois Van de Moortele;Xiaotong Zhang;Yicun Wang;Bin He
subject: EPT|electrical properties tomography|proton density|electrical properties|quantitative magnetic resonance imaging|magnetic resonance imaging (MRI)|proton density imaging|<formula formulatype="inline"><tex Notation="TeX">$B_{1}$</tex></formula> -mapping
Year: 2016
Publisher: IEEE
Abstract: Electrical conductivity and permittivity of biological tissues are important diagnostic parameters and are useful for calculating subject-specific specific absorption rate distribution. On the other hand, water proton density also has clinical relevance for diagnosis purposes. These two kinds of tissue properties are inevitably associated in the technique of electrical properties tomography (EPT), which can be used to map in vivo electrical properties based on the measured B1 field distribution at Larmor frequency using magnetic resonance imaging (MRI). The signal magnitude in MR images is locally proportional to both the proton density of tissue and the receive B1 field; this is a source of artifact in receive B1-based EPT reconstruction because these two quantities cannot easily be disentangled. In this study, a new method was proposed for simultaneously extracting quantitative conductivity, permittivity and proton density from the measured magnitude of transmit B1 field, proton density-weighted receive B1 field, and transceiver phase, in a multi-channel radiofrequency (RF) coil using MRI, without specific assumptions to derive the proton density distribution. We evaluated the spatial resolution, sensitivity to contrast, and accuracy of the method using numerical simulations of B1 field in a phantom and in a realistic human head model. Using the proposed method, conductivity, permittivity and proton density were then experimentally obtained ex vivo in a pork tissue sample on a 7T MRI scanner equipped with a 16-channel microstrip transceiver RF coil.
URI: http://localhost/handle/Hannan/183192
http://localhost/handle/Hannan/584160
ISSN: 0278-0062
1558-254X
volume: 35
issue: 9
Appears in Collections:2016

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Title: Simultaneous Quantitative Imaging of Electrical Properties and Proton Density From <formula formulatype="inline"><tex Notation="TeX"> B_{1} </tex></formula> Maps Using MRI
Authors: Jiaen Liu;Pierre-Francois Van de Moortele;Xiaotong Zhang;Yicun Wang;Bin He
subject: EPT|electrical properties tomography|proton density|electrical properties|quantitative magnetic resonance imaging|magnetic resonance imaging (MRI)|proton density imaging|<formula formulatype="inline"><tex Notation="TeX">$B_{1}$</tex></formula> -mapping
Year: 2016
Publisher: IEEE
Abstract: Electrical conductivity and permittivity of biological tissues are important diagnostic parameters and are useful for calculating subject-specific specific absorption rate distribution. On the other hand, water proton density also has clinical relevance for diagnosis purposes. These two kinds of tissue properties are inevitably associated in the technique of electrical properties tomography (EPT), which can be used to map in vivo electrical properties based on the measured B1 field distribution at Larmor frequency using magnetic resonance imaging (MRI). The signal magnitude in MR images is locally proportional to both the proton density of tissue and the receive B1 field; this is a source of artifact in receive B1-based EPT reconstruction because these two quantities cannot easily be disentangled. In this study, a new method was proposed for simultaneously extracting quantitative conductivity, permittivity and proton density from the measured magnitude of transmit B1 field, proton density-weighted receive B1 field, and transceiver phase, in a multi-channel radiofrequency (RF) coil using MRI, without specific assumptions to derive the proton density distribution. We evaluated the spatial resolution, sensitivity to contrast, and accuracy of the method using numerical simulations of B1 field in a phantom and in a realistic human head model. Using the proposed method, conductivity, permittivity and proton density were then experimentally obtained ex vivo in a pork tissue sample on a 7T MRI scanner equipped with a 16-channel microstrip transceiver RF coil.
URI: http://localhost/handle/Hannan/183192
http://localhost/handle/Hannan/584160
ISSN: 0278-0062
1558-254X
volume: 35
issue: 9
Appears in Collections:2016

Files in This Item:
File Description SizeFormat 
7442843.pdf1.56 MBAdobe PDFThumbnail
Preview File
Title: Simultaneous Quantitative Imaging of Electrical Properties and Proton Density From <formula formulatype="inline"><tex Notation="TeX"> B_{1} </tex></formula> Maps Using MRI
Authors: Jiaen Liu;Pierre-Francois Van de Moortele;Xiaotong Zhang;Yicun Wang;Bin He
subject: EPT|electrical properties tomography|proton density|electrical properties|quantitative magnetic resonance imaging|magnetic resonance imaging (MRI)|proton density imaging|<formula formulatype="inline"><tex Notation="TeX">$B_{1}$</tex></formula> -mapping
Year: 2016
Publisher: IEEE
Abstract: Electrical conductivity and permittivity of biological tissues are important diagnostic parameters and are useful for calculating subject-specific specific absorption rate distribution. On the other hand, water proton density also has clinical relevance for diagnosis purposes. These two kinds of tissue properties are inevitably associated in the technique of electrical properties tomography (EPT), which can be used to map in vivo electrical properties based on the measured B1 field distribution at Larmor frequency using magnetic resonance imaging (MRI). The signal magnitude in MR images is locally proportional to both the proton density of tissue and the receive B1 field; this is a source of artifact in receive B1-based EPT reconstruction because these two quantities cannot easily be disentangled. In this study, a new method was proposed for simultaneously extracting quantitative conductivity, permittivity and proton density from the measured magnitude of transmit B1 field, proton density-weighted receive B1 field, and transceiver phase, in a multi-channel radiofrequency (RF) coil using MRI, without specific assumptions to derive the proton density distribution. We evaluated the spatial resolution, sensitivity to contrast, and accuracy of the method using numerical simulations of B1 field in a phantom and in a realistic human head model. Using the proposed method, conductivity, permittivity and proton density were then experimentally obtained ex vivo in a pork tissue sample on a 7T MRI scanner equipped with a 16-channel microstrip transceiver RF coil.
URI: http://localhost/handle/Hannan/183192
http://localhost/handle/Hannan/584160
ISSN: 0278-0062
1558-254X
volume: 35
issue: 9
Appears in Collections:2016

Files in This Item:
File Description SizeFormat 
7442843.pdf1.56 MBAdobe PDFThumbnail
Preview File