Please use this identifier to cite or link to this item: http://localhost/handle/Hannan/273934
Title: Neuroepigenomics in Aging and Disease
Authors: Delgado-Morales, Raul. ;
subject: Life Sciences;Gene expression. ;;Medical genetics. ;;Proteomics. ;;Life Sciences;Proteomics. ;;Gene Expression. ;;Gene Function. ;;572.6 ; 23 ;;QD431-431.7 ;
Year: 2017
place: Cham :
Publisher: Springer International Publishing :
Imprint: Springer,
Series/Report no.: Advances in Experimental Medicine and Biology, ; 0065-2598 ; ; 978. ;
Advances in Experimental Medicine and Biology, ; 0065-2598 ; ; 978. ;
Abstract: Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the ??physiological epigenome?? are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system??s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington??s disease) and elderly (Alzheimer??s disease, Parkinson??s disease). The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on neuronal function and behavior. Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases. ;
Description: Printed edition: ; 9783319538884. ;




No author

No author
URI: http://localhost/handle/Hannan/273934
ISBN: 9783319538891 ;
9783319538884 (print) ;
More Information: XIII, 525 p. 41 illus., 39 illus. in color. ; online resource. ;
Appears in Collections:Chemistry

Files in This Item:
File SizeFormat 
9783319538891.pdf8.47 MBAdobe PDF
Title: Neuroepigenomics in Aging and Disease
Authors: Delgado-Morales, Raul. ;
subject: Life Sciences;Gene expression. ;;Medical genetics. ;;Proteomics. ;;Life Sciences;Proteomics. ;;Gene Expression. ;;Gene Function. ;;572.6 ; 23 ;;QD431-431.7 ;
Year: 2017
place: Cham :
Publisher: Springer International Publishing :
Imprint: Springer,
Series/Report no.: Advances in Experimental Medicine and Biology, ; 0065-2598 ; ; 978. ;
Advances in Experimental Medicine and Biology, ; 0065-2598 ; ; 978. ;
Abstract: Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the ??physiological epigenome?? are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system??s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington??s disease) and elderly (Alzheimer??s disease, Parkinson??s disease). The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on neuronal function and behavior. Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases. ;
Description: Printed edition: ; 9783319538884. ;




No author

No author
URI: http://localhost/handle/Hannan/273934
ISBN: 9783319538891 ;
9783319538884 (print) ;
More Information: XIII, 525 p. 41 illus., 39 illus. in color. ; online resource. ;
Appears in Collections:Chemistry

Files in This Item:
File SizeFormat 
9783319538891.pdf8.47 MBAdobe PDF
Title: Neuroepigenomics in Aging and Disease
Authors: Delgado-Morales, Raul. ;
subject: Life Sciences;Gene expression. ;;Medical genetics. ;;Proteomics. ;;Life Sciences;Proteomics. ;;Gene Expression. ;;Gene Function. ;;572.6 ; 23 ;;QD431-431.7 ;
Year: 2017
place: Cham :
Publisher: Springer International Publishing :
Imprint: Springer,
Series/Report no.: Advances in Experimental Medicine and Biology, ; 0065-2598 ; ; 978. ;
Advances in Experimental Medicine and Biology, ; 0065-2598 ; ; 978. ;
Abstract: Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the ??physiological epigenome?? are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system??s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington??s disease) and elderly (Alzheimer??s disease, Parkinson??s disease). The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on neuronal function and behavior. Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases. ;
Description: Printed edition: ; 9783319538884. ;




No author

No author
URI: http://localhost/handle/Hannan/273934
ISBN: 9783319538891 ;
9783319538884 (print) ;
More Information: XIII, 525 p. 41 illus., 39 illus. in color. ; online resource. ;
Appears in Collections:Chemistry

Files in This Item:
File SizeFormat 
9783319538891.pdf8.47 MBAdobe PDF